Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
DRD3 | P35462 | dopamine receptor D3 | G-protein coupled receptor | 2.4E-03 | 0.529 | 0.692 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
GBAP1 | glucosylceramidase beta pseudogene 1 | 0.623 | 0.538 | |||
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
MAOB | P27338 | monoamine oxidase B | 1.00 | 0.533 | 0.808 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
PDE10A | Q9Y233 | phosphodiesterase 10A | 1.00 | 0.619 | 0.615 | |
PINK1 | Q9BXM7 | PTEN induced kinase 1 | Kinase | 1.9E-10 | 0.516 | 0.769 |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SNCB | Q16143 | synuclein beta | Transporter | 6.8E-02 | 0.619 | 0.577 |
SNCG | O76070 | synuclein gamma | Transporter | 8.5E-04 | 0.550 | 0.615 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
TH | P07101 | tyrosine hydroxylase | 1.7E-06 | 0.462 | 0.885 | |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |