Disease: Alzheimer Disease, Late Onset
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
HLA-DRA P01903 major histocompatibility complex, class II, DR alpha Immune response 0.52 0.581 0.769
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808