Disease: Dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CHCHD2 Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 1.7E-07 0.638 0.538
CHM P24386 CHM Rab escort protein Enzyme 1.00 0.592 0.654
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
EIF4G1 Q04637 eukaryotic translation initiation factor 4 gamma 1 Nucleic acid binding 1.00 0.553 0.808
FASTK Q14296 Fas activated serine/threonine kinase Kinase 4.7E-03 0.617 0.615
FBXO7 Q9Y3I1 F-box protein 7 5.8E-07 0.650 0.769
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808