Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
LAMP2 P13473 lysosomal associated membrane protein 2 Transporter 0.27 0.552 0.731
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SNCB Q16143 synuclein beta Transporter 6.8E-02 0.619 0.577
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923