Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
BCKDK | O14874 | branched chain keto acid dehydrogenase kinase | Kinase | 5.7E-05 | 0.769 | 0.154 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
CBLL2 | Q8N7E2 | Cbl proto-oncogene like 2 | Enzyme | 0.476 | 0.808 | |
CHCHD2 | Q9Y6H1 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 1.7E-07 | 0.638 | 0.538 | |
CTSD | P07339 | cathepsin D | Enzyme | 9.2E-04 | 0.478 | 0.846 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
DNM1L | O00429 | dynamin 1 like | Enzyme modulator | 5.7E-04 | 0.475 | 0.808 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
HSPA4 | P34932 | heat shock protein family A (Hsp70) member 4 | 1.00 | 0.394 | 0.923 | |
LAMP2 | P13473 | lysosomal associated membrane protein 2 | Transporter | 0.27 | 0.552 | 0.731 |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
MUL1 | Q969V5 | mitochondrial E3 ubiquitin protein ligase 1 | 1.9E-06 | 0.473 | 0.808 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SNCB | Q16143 | synuclein beta | Transporter | 6.8E-02 | 0.619 | 0.577 |
SNCG | O76070 | synuclein gamma | Transporter | 8.5E-04 | 0.550 | 0.615 |
STX1B | P61266 | syntaxin 1B | Transporter | 0.99 | 0.650 | 0.308 |