Disease: Tauopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CAST P20810 calpastatin 4.1E-12 0.541 0.846
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
DYRK1A Q13627 dual specificity tyrosine phosphorylation regulated kinase 1A Kinase 1.00 0.533 0.769
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962