Disease: Acute Megakaryocytic Leukemias
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808
GFI1B Q5VTD9 growth factor independent 1B transcriptional repressor 5.2E-04 0.623 0.500
GP1BA P07359 glycoprotein Ib platelet subunit alpha Receptor 3.2E-03 0.565 0.692
HBG1 P69891 hemoglobin subunit gamma 1 0.57 0.615 0.538
HBG2 P69892 hemoglobin subunit gamma 2 0.67 0.565 0.692
IL11 P20809 interleukin 11 3.2E-04 0.481 0.808
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IL6 P05231 interleukin 6 0.32 0.248 0.962
ITGA2B P08514 integrin subunit alpha 2b 1.5E-16 0.493 0.692
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
MIR486-1 microRNA 486-1 0.521 0.808
NME1 P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 3.2E-03 0.443 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846
PF4 P02776 platelet factor 4 Signaling 4.3E-02 0.522 0.846