Disease: Thrombocythemia, Essential
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
FLII Q13045 FLII actin remodeling protein 5.5E-12 0.520 0.808
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IL6 P05231 interleukin 6 0.32 0.248 0.962
ITGA2B P08514 integrin subunit alpha 2b 1.5E-16 0.493 0.692
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
MTUS1 Q9ULD2 microtubule associated scaffold protein 1 3.6E-11 0.626 0.577
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923