Disease: Turcot syndrome (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALCAM Q13740 activated leukocyte cell adhesion molecule Cell adhesion 0.73 0.502 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BAAT Q14032 bile acid-CoA:amino acid N-acyltransferase 7.9E-08 0.578 0.654
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MUC2 Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 9.4E-10 0.486 0.808
MUC5AC P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 1.0E-08 0.483 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808