Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
MTCO2P12 | MT-CO2 pseudogene 12 | 0.368 | 0.962 | |||
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
MRC1 | P22897 | mannose receptor C-type 1 | 0.94 | 0.413 | 0.846 | |
BAX | Q07812 | BCL2 associated X, apoptosis regulator | Signaling | 0.32 | 0.417 | 0.885 |
PSMD9 | O00233 | proteasome 26S subunit, non-ATPase 9 | Enzyme modulator | 4.9E-06 | 0.435 | 0.846 |
TMED7 | Q86XR7 Q9Y3B3 | transmembrane p24 trafficking protein 7 | Transporter | 0.48 | 0.436 | 0.808 |
IFI27 | P40305 | interferon alpha inducible protein 27 | 1.1E-02 | 0.437 | 0.769 | |
TICAM2 | Q86XR7 Q9Y3B3 | toll like receptor adaptor molecule 2 | 2.6E-03 | 0.438 | 0.769 | |
TMED7-TICAM2 | Q86XR7 Q9Y3B3 | TMED7-TICAM2 readthrough | 2.6E-03 | 0.438 | 0.769 | |
DCTN6 | O00399 | dynactin subunit 6 | Cellular structure | 5.6E-02 | 0.442 | 0.769 |
ZNRD2 | O60232 | zinc ribbon domain containing 2 | 1.8E-07 | 0.443 | 0.769 | |
H3P23 | H3 histone pseudogene 23 | 0.443 | 0.769 | |||
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |