Disease: Acidosis, Lactic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACAD9 Q9H845 acyl-CoA dehydrogenase family member 9 Enzyme 4.5E-08 0.722 0.269
ATAD3A Q9NVI7 ATPase family AAA domain containing 3A Enzyme 4.1E-09 0.628 0.692
BOLA3 Q53S33 bolA family member 3 0.15 0.760 0.231
COA6 Q5JTJ3 cytochrome c oxidase assembly factor 6 5.7E-03 0.805 0.192
COX15 Q7KZN9 cytochrome c oxidase assembly homolog COX15 1.1E-13 0.638 0.538
CYTB P00156 cytochrome b 0.529 0.808
ELAC2 Q9BQ52 elaC ribonuclease Z 2 1.7E-20 0.670 0.346
GTPBP3 Q969Y2 GTP binding protein 3, mitochondrial 4.2E-09 0.805 0.154
KARS1 Q15046 lysyl-tRNA synthetase 1 Enzyme 4.2E-09 0.636 0.577
MGAM O43451 maltase-glucoamylase Enzyme 1.0E-35 0.592 0.615
MRPS14 O60783 mitochondrial ribosomal protein S14 Nucleic acid binding 1.6E-04 0.805 0.231
MRPS22 P82650 mitochondrial ribosomal protein S22 1.5E-05 0.638 0.500
MTO1 Q9Y2Z2 mitochondrial tRNA translation optimization 1 7.4E-06 0.670 0.462
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
NDUFS1 P28331 NADH:ubiquinone oxidoreductase core subunit S1 Enzyme 6.6E-11 0.595 0.692
NDUFV2 P19404 NADH:ubiquinone oxidoreductase core subunit V2 5.6E-03 0.610 0.500
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
SCO1 O75880 synthesis of cytochrome C oxidase 1 Enzyme 2.2E-04 0.638 0.769
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
SI P14410 sucrase-isomaltase Enzyme 3.9E-60 0.569 0.692
SUCLG1 P53597 succinate-CoA ligase GDP/ADP-forming subunit alpha 4.8E-04 0.666 0.423
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
TMEM70 Q9BUB7 transmembrane protein 70 2.9E-02 0.636 0.654
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TTR P02766 transthyretin Transporter 0.52 0.423 0.885