Disease: Arrhythmogenic Right Ventricular Dysplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACTN2 P35609 actinin alpha 2 1.00 0.686 0.462
ANKRD1 Q15327 ankyrin repeat domain 1 2.6E-10 0.628 0.692
DES P17661 desmin 8.8E-03 0.460 0.846
DSG2 Q14126 desmoglein 2 Cell adhesion 2.8E-10 0.601 0.692
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
FLNC Q14315 filamin C 1.00 0.568 0.615
HCN4 Q9Y3Q4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 Ion channel 1.00 0.617 0.269
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
LMNA P02545 lamin A/C 1.00 0.384 0.885
MEF2C Q06413 myocyte enhancer factor 2C Transcription factor 1.7E-02 0.517 0.769
MYBPC3 Q14896 myosin binding protein C3 8.0E-11 0.593 0.385
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
OBSCN Q5VST9 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF Kinase 1.9E-164 0.736 0.538
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PLN P26678 phospholamban 0.45 0.595 0.577
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRB1 P04280 proline rich protein BstNI subfamily 1 (gene/pseudogene) 8.4E-11 0.621 0.692
PRKAG2 Q9UGJ0 protein kinase AMP-activated non-catalytic subunit gamma 2 Enzyme modulator 1.00 0.582 0.654
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615
SCN10A Q9Y5Y9 sodium voltage-gated channel alpha subunit 10 Ion channel 9.9E-38 0.566 0.692