Disease: Congenital clubfoot
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AP4S1 Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 1.7E-06 0.674 0.385
AP4E1 Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 2.8E-03 0.656 0.385
HOXC@ homeobox C cluster 0.695 0.462
TBX15 Q96SF7 T-box transcription factor 15 Transcription factor 0.66 0.603 0.500
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500
WDR73 Q6P4I2 WD repeat domain 73 2.8E-09 0.610 0.500
ATP6V1A P38606 ATPase H+ transporting V1 subunit A Transporter 0.87 0.579 0.615
AKR1C1 Q04828 aldo-keto reductase family 1 member C1 Enzyme 3.5E-15 0.593 0.615
MYL2 P10916 myosin light chain 2 Calcium-binding protein 2.7E-08 0.601 0.615
GSC P56915 goosecoid homeobox 1.4E-02 0.631 0.615
ITGA7 Q13683 integrin subunit alpha 7 4.3E-17 0.588 0.654
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654
WNT7A O00755 Wnt family member 7A Signaling 3.6E-02 0.531 0.692
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692
ATP6V0A2 Q9Y487 ATPase H+ transporting V0 subunit a2 Transporter 2.6E-11 0.570 0.692
SELENON Q9NZV5 selenoprotein N 9.8E-10 0.575 0.692
TBX4 P57082 T-box transcription factor 4 Transcription factor 0.50 0.576 0.731
BICD2 Q8TD16 BICD cargo adaptor 2 0.98 0.615 0.731
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
ACTA1 P68133 actin alpha 1, skeletal muscle Cellular structure 1.1E-06 0.540 0.769
ATP6V1E1 P36543 ATPase H+ transporting V1 subunit E1 Transporter 0.53 0.610 0.769
GPC4 O75487 glypican 4 0.93 0.547 0.769
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
MAP3K20 Q9NYL2 mitogen-activated protein kinase kinase kinase 20 Kinase 8.4E-09 0.564 0.769
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769