Disease: Retinoblastoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAFK O60675 MAF bZIP transcription factor K Transcription factor 0.71 0.592 0.654
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
DHFR P00374 dihydrofolate reductase Enzyme 3.4E-02 0.513 0.808
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
PDGFA P04085 platelet derived growth factor subunit A Signaling 0.81 0.533 0.731
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962