Disease: Frontotemporal dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
GNE Q9Y223 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Enzyme 2.5E-16 0.610 0.692
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
CLU P10909 clusterin 7.8E-05 0.426 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
TUBA4A P68366 tubulin alpha 4a Cellular structure 0.16 0.751 0.269
TAF15 Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 0.17 0.626 0.500
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
RBMS3 Q6XE24 RNA binding motif single stranded interacting protein 3 0.21 0.553 0.692
PNO1 Q9NRX1 partner of NOB1 homolog 0.23 0.564 0.615
PFN1 P07737 profilin 1 0.73 0.565 0.769