Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 8.1E-21 0.615 0.423
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LY6E Q16553 lymphocyte antigen 6 family member E 0.32 0.563 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PRPH P41219 peripherin 4.8E-14 0.623 0.462
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962