Disease: Pick Disease of the Brain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRIA3 P42263 glutamate ionotropic receptor AMPA type subunit 3 Ion channel 1.00 0.566 0.692
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
MAK16 Q9BXY0 MAK16 homolog 0.96 0.566 0.615
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MATR3 P43243 matrin 3 1.00 0.631 0.538
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PNO1 Q9NRX1 partner of NOB1 homolog 0.23 0.564 0.615
PRDX2 P32119 peroxiredoxin 2 Enzyme 8.7E-02 0.474 0.885
PRDX6 P30041 peroxiredoxin 6 Enzyme 4.8E-05 0.572 0.731
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923