Disease: Amyotrophic Lateral Sclerosis, Sporadic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 8.1E-21 0.615 0.423
ATXN1 P54253 ataxin 1 0.97 0.534 0.769
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885
BSG P35613 basigin (Ok blood group) 2.6E-05 0.458 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CALB2 P22676 calbindin 2 Calcium-binding protein 4.5E-07 0.545 0.692
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CD68 P34810 CD68 molecule Transporter 1.4E-06 0.408 0.808
CD7 P09564 CD7 molecule 5.1E-02 0.722 0.385
CLU P10909 clusterin 7.8E-05 0.426 0.885
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
DBX1 A6NMT0 developing brain homeobox 1 6.1E-02 0.890 0.077
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
FGF6 P10767 fibroblast growth factor 6 Signaling 4.0E-04 0.729 0.308
FMO1 Q01740 flavin containing dimethylaniline monoxygenase 1 Enzyme 9.1E-11 0.805 0.269
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577
GBX2 P52951 gastrulation brain homeobox 2 Transcription factor 0.71 0.751 0.385