Disease: GRN-related frontotemporal dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
MAK16 Q9BXY0 MAK16 homolog 0.96 0.566 0.615
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MATR3 P43243 matrin 3 1.00 0.631 0.538
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PNO1 Q9NRX1 partner of NOB1 homolog 0.23 0.564 0.615
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
RBMS3 Q6XE24 RNA binding motif single stranded interacting protein 3 0.21 0.553 0.692
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SRRM2 Q9UQ35 serine/arginine repetitive matrix 2 1.00 0.564 0.692
TAF15 Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 0.17 0.626 0.500
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846