Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
VCP P55072 valosin containing protein 1.00 0.469 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
TSHR P16473 thyroid stimulating hormone receptor G-protein coupled receptor 3.0E-15 0.486 0.808
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808