Disease: Blindness
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND2 P03891 MTND2 0.601 0.615
ND3 P03897 NADH dehydrogenase, subunit 3 (complex I) 0.604 0.654
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
NR2E3 Q9Y5X4 nuclear receptor subfamily 2 group E member 3 Nuclear receptor 0.603 0.500
KIZ Q2M2Z5 kizuna centrosomal protein 0.722 0.308
USH2A O75445 usherin Enzyme modulator 1.6E-94 0.579 0.692
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
ABCA4 P78363 ATP binding cassette subfamily A member 4 Transporter 5.3E-48 0.493 0.769
EYS Q5T1H1 eyes shut homolog 3.7E-41 0.631 0.538
MYO7A Q13402 myosin VIIA Cellular structure 1.6E-38 0.585 0.423
CNGB1 Q14028 cyclic nucleotide gated channel subunit beta 1 Ion channel 1.8E-37 0.628 0.538
IFT172 Q9UG01 intraflagellar transport 172 Cellular structure 3.3E-33 0.582 0.654
TYR P14679 tyrosinase Enzyme 5.0E-32 0.473 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692
PDE6B P35913 phosphodiesterase 6B 2.6E-27 0.626 0.346
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
PDE6A P16499 phosphodiesterase 6A 6.6E-25 0.691 0.269
CERKL Q49MI3 ceramide kinase like 9.8E-25 0.678 0.308
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
IFT140 Q96RY7 intraflagellar transport 140 Cellular structure 9.9E-24 0.572 0.692
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846