DisGeNET - a database of gene-disease associations

List of shared genes

Metastatic human epidermal growth factor 2 positive carcinoma of breast, C4721209

Disease: Skin toxicity

Source: ALL

Results per page

Gene

Disease

Variant

Source

DSI _v

DPI _v

pLI

Protein Class

Gene	Uniprot	Gene Full Name	Protein Class	pLI	DSI _v	DPI _v
ABCB1	P08183	ATP binding cassette subfamily B member 1	Transporter	1.3E-05	0.344	0.885
AREG	P15514	amphiregulin	Signaling	0.35	0.487	0.769
CCND1	P24385	cyclin D1	Enzyme modulator	0.89	0.344	0.923
EGFR	P00533	epidermal growth factor receptor	Kinase	0.37	0.295	0.885
FCGR3A	P08637	Fc fragment of IgG receptor IIIa	Cell adhesion	3.7E-06	0.432	0.962
HGF	P14210	hepatocyte growth factor	Enzyme	1.00	0.374	0.885
JAK2	O60674	Janus kinase 2	Kinase	0.65	0.385	0.885
PIK3CA	P42336	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Kinase	1.00	0.292	0.923
PIK3CB	P42338	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Kinase	1.00	0.322	0.885
PIK3CD	O00329	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Kinase	1.00	0.319	0.885
PIK3CG	P48736	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma	Kinase	1.4E-06	0.320	0.885
TP53	P04637	tumor protein p53	Transcription factor	0.53	0.236	0.962