Disease: Breast Cancer, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
BABAM1 Q9NWV8 BRISC and BRCA1 A complex member 1 0.96 0.678 0.385
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRD7 Q9NPI1 bromodomain containing 7 Epigenetic regulator 1.00 0.638 0.500
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
CD24 P25063 CD24 molecule 0.472 0.769
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923