Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
HLA-DQB1 | P01920 | major histocompatibility complex, class II, DQ beta 1 | Immune response | 8.9E-03 | 0.407 | 0.885 |
ERCC2 | P18074 | ERCC excision repair 2, TFIIH core complex helicase subunit | Enzyme | 7.1E-20 | 0.420 | 0.846 |
TLR9 | Q9NR96 | toll like receptor 9 | 9.8E-06 | 0.411 | 0.885 | |
ABCG2 | Q9UNQ0 | ATP binding cassette subfamily G member 2 (Junior blood group) | Transporter | 2.1E-32 | 0.419 | 0.885 |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
PTK2B | Q14289 | protein tyrosine kinase 2 beta | Kinase | 0.94 | 0.448 | 0.808 |
RETN | Q9HD89 | resistin | 3.7E-02 | 0.454 | 0.808 | |
MIR200C | microRNA 200c | 0.486 | 0.846 | |||
SF3B1 | O75533 | splicing factor 3b subunit 1 | Nucleic acid binding | 1.00 | 0.511 | 0.731 |
XRCC4 | Q13426 | X-ray repair cross complementing 4 | 8.3E-07 | 0.528 | 0.769 | |
TP53BP1 | Q12888 | tumor protein p53 binding protein 1 | Epigenetic regulator | 1.00 | 0.520 | 0.731 |
SLCO1B1 | Q9Y6L6 | solute carrier organic anion transporter family member 1B1 | Transporter | 1.1E-21 | 0.538 | 0.731 |
CRB3 | Q9BUF7 | crumbs cell polarity complex component 3 | 0.36 | 0.716 | 0.308 | |
WSB1 | Q9Y6I7 | WD repeat and SOCS box containing 1 | 0.42 | 0.760 | 0.269 |