Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
S100B | P04271 | S100 calcium binding protein B | Calcium-binding protein | 4.4E-02 | 0.383 | 0.923 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
PRL | P01236 | prolactin | Signaling | 2.9E-07 | 0.406 | 0.885 |
PDCD1 | Q15116 | programmed cell death 1 | 0.42 | 0.402 | 0.846 | |
GATA3 | P23771 | GATA binding protein 3 | 0.90 | 0.415 | 0.846 | |
CEACAM5 | P06731 | CEA cell adhesion molecule 5 | 4.2E-10 | 0.420 | 0.846 | |
HMGA2 | P52926 | high mobility group AT-hook 2 | Nucleic acid binding | 0.87 | 0.429 | 0.808 |
ROS1 | P08922 | ROS proto-oncogene 1, receptor tyrosine kinase | Kinase | 1.6E-72 | 0.439 | 0.885 |
KRT19 | P08727 | keratin 19 | 4.3E-03 | 0.460 | 0.731 | |
F2RL1 | P55085 | F2R like trypsin receptor 1 | G-protein coupled receptor | 1.5E-04 | 0.480 | 0.769 |
ENO2 | P09104 | enolase 2 | Enzyme | 0.38 | 0.475 | 0.846 |
MUC16 | Q8WXI7 | mucin 16, cell surface associated | 8.3E-112 | 0.479 | 0.808 | |
ACTA2 | P62736 | actin alpha 2, smooth muscle | Cellular structure | 0.93 | 0.508 | 0.846 |
CD74 | P04233 | CD74 molecule | Enzyme modulator | 0.25 | 0.512 | 0.808 |