Gene: CTNNB1 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure. 1999432

1991
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure. 1999432

1991
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure. 1999432

1991
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR The product of the Drosophila segment polarity gene armadillo is part of a multi-protein complex resembling the vertebrate adherens junction. 8227220

1993
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR The product of the Drosophila segment polarity gene armadillo is part of a multi-protein complex resembling the vertebrate adherens junction. 8227220

1993
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR The product of the Drosophila segment polarity gene armadillo is part of a multi-protein complex resembling the vertebrate adherens junction. 8227220

1993
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR Lack of beta-catenin affects mouse development at gastrulation. 8582267

1995
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR Lack of beta-catenin affects mouse development at gastrulation. 8582267

1995
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR Lack of beta-catenin affects mouse development at gastrulation. 8582267

1995
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway. 9060476

1997
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway. 9060476

1997
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway. 9060476

1997
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. 11719191

2001
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. 11719191

2001
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. 11719191

2001
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. 15866163

2005
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. 15866164

2005
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR Wnt/beta-catenin pathway. 15713948

2005
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR Wnt/beta-catenin pathway. 15713948

2005
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. 15866164

2005
dbSNP: rs1553631783
rs1553631783
CTNNB1
A 0.700 CausalMutation CLINVAR Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. 15866163

2005
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR Wnt/beta-catenin pathway. 15713948

2005
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. 15866163

2005
dbSNP: rs797044875
rs797044875
CTNNB1
A 0.700 GeneticVariation CLINVAR Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. 15866164

2005
dbSNP: rs1553631770
rs1553631770
CTNNB1
T 0.700 GeneticVariation CLINVAR Crystal structure of a full-length beta-catenin. 18334222

2008