|
rs11209026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031).
|
31044631 |
2019 |
|
rs1800629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031).
|
31044631 |
2019 |
|
rs213950
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the aim of our study was to determine the functional importance of common cystic fibrosis transmembrane conductance regulator variations IVS8-poly T, R117H, and M470V for the severity of acute pancreatitis.
|
30132293 |
2019 |
|
rs78655421
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the aim of our study was to determine the functional importance of common cystic fibrosis transmembrane conductance regulator variations IVS8-poly T, R117H, and M470V for the severity of acute pancreatitis.
|
30132293 |
2019 |
|
rs4251961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL1RN -1129T>C (rs4251961) genotypes might be associated with a significant increase of AP risk in a Korean ethnic group.
|
29117667 |
2018 |
|
rs1052571
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05).
|
27984487 |
2017 |
|
rs1132312
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05).
|
27984487 |
2017 |
|
rs121912654
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men.
|
27984487 |
2017 |
|
rs142907823
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05).
|
27984487 |
2017 |
|
rs1490931437
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05).
|
27984487 |
2017 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men.
|
27984487 |
2017 |
|
rs1805017
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results demonstrated that the LP-PLA2 gene polymorphisms, V279F and R92H, may be associated with susceptibility to and severity of AP.
|
28332853 |
2017 |
|
rs497078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to determine the relationship between the presence of p.G60 = polymorphism (c.180C > T; rs497078) CTRC and the incidence together with the clinical course of acute pancreatitis (AP).
|
28095786 |
2017 |
|
rs76863441
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results demonstrated that the LP-PLA2 gene polymorphisms, V279F and R92H, may be associated with susceptibility to and severity of AP.
|
28332853 |
2017 |
|
rs778574118
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men.
|
27984487 |
2017 |
|
rs5707
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The renin rs5707 G (rather than A) allele was associated with AP (P = 0.002), infected necrosis (P = 0.025) and mortality (P = 0.046).
|
24743610 |
2015 |
|
rs5743795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, TLR6 rs5743795 GG genotype patients had a lower risk for severe AP (GG OR, 0.909; P < 0.05).
|
25423559 |
2015 |
|
rs9904341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, we found that the survivin rs9904341 polymorphism was associated with an increased risk of acute pancreatitis.
|
26125713 |
2015 |
|
rs1451659304
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The data from this study showed that compound heterozygote mutations of A98T and L279V inactivate lipoprotein lipase enzymatic activity and contribute to severe HTG and acute pancreatitis in two Chinese patients.
|
24646025 |
2014 |
|
rs145657341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The data from this study showed that compound heterozygote mutations of A98T and L279V inactivate lipoprotein lipase enzymatic activity and contribute to severe HTG and acute pancreatitis in two Chinese patients.
|
24646025 |
2014 |
|
rs371282890
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The data from this study showed that compound heterozygote mutations of A98T and L279V inactivate lipoprotein lipase enzymatic activity and contribute to severe HTG and acute pancreatitis in two Chinese patients.
|
24646025 |
2014 |
|
rs4986791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our current meta-analysis suggests that TLR4 Asp299Gly and Thr399Ile polymorphisms may not be risk factors to AP susceptibility.
|
24914392 |
2014 |
|
rs5029924
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Neither of these SNPs was associated with susceptibility to AP; however, acute pancreatitis patients who possessed the T allele of rs5029924 were more likely to experience systemic inflammatory response syndrome.
|
25050625 |
2014 |
|
rs773891125
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The data from this study showed that compound heterozygote mutations of A98T and L279V inactivate lipoprotein lipase enzymatic activity and contribute to severe HTG and acute pancreatitis in two Chinese patients.
|
24646025 |
2014 |
|
rs16944
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, there were no significant associations between IL-1β (IL-1β +3954 C/T (rs1143634) and IL-1β -511 C/T (rs16944)), IL-6 (IL-6 -174 G/C (rs1800795) and IL-6 -634 C/G (rs1800796)) and IL-10 (IL-10 -1082 A/G (rs1800896), IL-10 -819 C/T (rs1800871) and IL-10 -592 C/A (rs1800872)) gene polymorphisms and AP risk.
|
24072654 |
2013 |