|
rs28934575
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs542027040
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One eccrine gland adenocarcinoma showed allelic loss of 17p and a Cys 176 Arg mutation in the p53 gene.
|
10660129 |
2000 |
|
rs967461896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One eccrine gland adenocarcinoma showed allelic loss of 17p and a Cys 176 Arg mutation in the p53 gene.
|
10660129 |
2000 |
|
rs143752852
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A mutation (T915C: L296P) was found in an adenocarcinoma specimen.
|
10959094 |
2000 |
|
rs199769221
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results show that the Arg117His mutation does not contribute to pathogenesis of a substantial fraction of all pancreatic adenocarcinomas.
|
11062709 |
2000 |
|
rs1443465532
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results demonstrate that P125A endostatin inhibits the angiogenic switch during mammary gland adenocarcinoma tumor progression in the C3(1)/Tag transgenic model.
|
12209972 |
2002 |
|
rs876658657
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no significant association between the hMLH1 -93G-->A genotype and the risk for adenocarcinoma or small cell carcinoma.
|
15382050 |
2004 |
|
rs587782289
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An SNP, Thr706Ala, in the POLI gene encoding another translesion DNA polymerase was associated with adenocarcinoma and squamous cell carcinoma risk, particularly in individuals of ages < 61 years (OR Ala/Ala + Ala/Thr vs. Thr/Thr = 1.5 and 2.4, respectively).
|
15609317 |
2005 |
|
rs8305
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An SNP, Thr706Ala, in the POLI gene encoding another translesion DNA polymerase was associated with adenocarcinoma and squamous cell carcinoma risk, particularly in individuals of ages < 61 years (OR Ala/Ala + Ala/Thr vs. Thr/Thr = 1.5 and 2.4, respectively).
|
15609317 |
2005 |
|
rs33917957
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Specific expression of phospho-Met (p-Met) [Y1003] and [Y1230/1234/1235] was seen by immunohistochemistry. p-Met expression was preferentially observed at the NSCLC tumor invasive fronts. c-Met alterations were identified within the semaphorin domain (E168D, L299F, S323G, and N375S) and the juxtamembrane domain (R988C, R988C + T1010I, S1058P, and alternative splice product skipping entire juxtamembrane domain) of a NSCLC cell line and adenocarcinoma tissues.
|
15735036 |
2005 |
|
rs1057519847
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The L858R mutation was significantly correlated with gender (women versus men, P < 0.0001), Brinkman index (600 < or = versus 600, P = 0.001), pathologic subtypes (adenocarcinoma versus nonadenocarcinoma, P = 0.007), and differentiation status of the lung cancers (well versus moderately or poorly, P = 0.0439), whereas the deletion mutants were not.
|
15837743 |
2005 |
|
rs1057519848
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The L858R mutation was significantly correlated with gender (women versus men, P < 0.0001), Brinkman index (600 < or = versus 600, P = 0.001), pathologic subtypes (adenocarcinoma versus nonadenocarcinoma, P = 0.007), and differentiation status of the lung cancers (well versus moderately or poorly, P = 0.0439), whereas the deletion mutants were not.
|
15837743 |
2005 |
|
rs121434568
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The L858R mutation was significantly correlated with gender (women versus men, P < 0.0001), Brinkman index (600 < or = versus 600, P = 0.001), pathologic subtypes (adenocarcinoma versus nonadenocarcinoma, P = 0.007), and differentiation status of the lung cancers (well versus moderately or poorly, P = 0.0439), whereas the deletion mutants were not.
|
15837743 |
2005 |
|
rs1799782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194Trp polymorphism and lung cancer risk among heavy smokers remained robust given prior probabilities of 25% (FPRP = 0.238) and 10% (FPRP = 0.276), respectively.
|
15840879 |
2005 |
|
rs746702110
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The associations between the OGG1 Cys/Cys genotype and adenocarcinoma risk and between XRCC1 Arg194Trp polymorphism and lung cancer risk among heavy smokers remained robust given prior probabilities of 25% (FPRP = 0.238) and 10% (FPRP = 0.276), respectively.
|
15840879 |
2005 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This is the first report that the XRCC1 Arg399Gln polymorphism might be important in relation to the risk of adenocarcinoma/adenosquamous carcinoma of the cervix.
|
15990162 |
2005 |
|
rs1048943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CYP1A1 Ile462Val and MPO G-463A interact to increase risk of adenocarcinoma but not squamous cell carcinoma of the lung.
|
16195240 |
2006 |
|
rs125555
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For the MBD1 -501delT and Pro(401)Ala polymorphisms, the -501 T/T genotype was associated with a marginal significantly increased risk of adenocarcinoma compared with the -501(-/-) genotype (adjusted OR, 2.07; 95% CI, 1.02-4.20; P = 0.045), and the Pro/Pro genotype was associated with a significantly increased risk of adenocarcinoma compared with the Ala/Ala genotype (adjusted OR, 3.41; 95% CI, 1.21-9.60; P = 0.02).
|
16284366 |
2005 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In exon 15, one BRAF mutation (1796 thymine to adenine; V599E) was found in nonsmoking woman with well-differentiated adenocarcinoma.
|
16376942 |
2006 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In exon 15, one BRAF mutation (1796 thymine to adenine; V599E) was found in nonsmoking woman with well-differentiated adenocarcinoma.
|
16376942 |
2006 |
|
rs397517132
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In exon 15, one BRAF mutation (1796 thymine to adenine; V599E) was found in nonsmoking woman with well-differentiated adenocarcinoma.
|
16376942 |
2006 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The V600E mutation of the B-RAF gene was analyzed using allele-specific polymerase chain reaction in 79 archival prostatic adenocarcinomas (pT1aG1 to pT3cG3, median Gleason score 6); exons 11 and 15 were sequenced.
|
16413100 |
2006 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The V600E mutation of the B-RAF gene was analyzed using allele-specific polymerase chain reaction in 79 archival prostatic adenocarcinomas (pT1aG1 to pT3cG3, median Gleason score 6); exons 11 and 15 were sequenced.
|
16413100 |
2006 |
|
rs1057519847
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two weeks after induction with doxycycline, mice that express the EGFR(L858R) allele show diffuse lung cancer highly reminiscent of human bronchioloalveolar carcinoma and later develop interspersed multifocal adenocarcinomas.
|
16705038 |
2006 |
|
rs1057519848
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Two weeks after induction with doxycycline, mice that express the EGFR(L858R) allele show diffuse lung cancer highly reminiscent of human bronchioloalveolar carcinoma and later develop interspersed multifocal adenocarcinomas.
|
16705038 |
2006 |