Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | BEFREE | A fixed-effect model was chosen, and the pooled result showed that rs6296 was not related to al</span>coholism (z = 1.93, <i>p</i> = .053). | 31510870 | 2019 |
||||
|
0.080 | GeneticVariation | BEFREE | In the Southwestern American Indian tribe, significant sib pair linkage of antisocial alcoholism</span> to HTR1B G861C (P=.01) was again observed, and there was also significant linkage to D6S284 (P=.01). | 9819067 | 1998 |
||||
|
0.080 | GeneticVariation | BEFREE | There exists preliminary evidence for association of G861C with i) antisocial alcoholism in the Finnish; ii) alcoholism in the presence of inactive aldehyde dehydrogenase 2 in the Japanese; iii) a history of suicide attempts in European-American personality disorder patients; and iv) minimum lifetime body mass index in Canadian bulimia nervosa patients. | 12437478 | 2002 |
||||
|
0.080 | GeneticVariation | BEFREE | The aim of this study is to investigate the role of the most relevant variants (rs11568817, rs130058, rs6296 and rs13212041) of the HTR1B gene in the susceptibility to alcohol dependence. | 22005095 | 2012 |
||||
|
0.080 | GeneticVariation | BEFREE | Our study suggests that neither the 5-HTTLPR gene nor the 5-HT1B G861C polymorphism alone is a risk factor for antisocial alcoholism in Taiwan's Han Chinese population, but that the interaction between both genes may increase susceptibility to antisocial alcoholism. | 22550993 | 2012 |
||||
|
0.080 | GeneticVariation | BEFREE | The HTR1B 861G>C receptor polymorphism among patients suffering from alcoholism, major depression, anxiety disorders and narcolepsy. | 11104852 | 2000 |
||||
|
0.080 | GeneticVariation | BEFREE | No significant association of the genotype or allele frequencies of the h5-HTR(1B) G861C locus was observed with diagnoses of alcoholism, bipolar disorder, schizophrenia or a history of a suicide attempt. | 12496953 | 2003 |
||||
|
0.080 | GeneticVariation | BEFREE | Consequently, genes encoding serotonin (5-HT) receptors are candidates for genetic studies of both disorders. found evidence for linkage of antisocial alcoholism to HTR1B (the locus encoding the 5-HT1B receptor) in both Finns and Southwestern American Indians, and of allelic association of a G861C polymorphism at that locus with antisocial alcoholism in Finns. | 11751038 | 2002 |