Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs429358
rs429358
APOE
C 0.890 GeneticVariation CLINVAR

dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
G 0.800 CausalMutation CLINVAR

dbSNP: rs63751039
rs63751039
APP
0.790 GeneticVariation UNIPROT

dbSNP: rs193922916
rs193922916
APP
A 0.740 CausalMutation CLINVAR

dbSNP: rs63750973
rs63750973
APP
0.720 GeneticVariation UNIPROT

dbSNP: rs63751122
rs63751122
APP
0.710 GeneticVariation UNIPROT

dbSNP: rs1561901881
rs1561901881
CSF1R
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1561905293
rs1561905293
CSF1R
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1566630910
rs1566630910
PSEN1
A 0.700 CausalMutation CLINVAR

dbSNP: rs1566638673
rs1566638673
PSEN1
CTTA 0.700 GeneticVariation CLINVAR

dbSNP: rs1566656702
rs1566656702
PSEN1
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1566657804
rs1566657804
PSEN1
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1567885728
rs1567885728
GRN
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1568339995
rs1568339995
MAPT
T 0.700 GeneticVariation CLINVAR

dbSNP: rs377498269
rs377498269
SORL1
0.700 GeneticVariation UNIPROT

dbSNP: rs63750009
rs63750009
PSEN1
C 0.700 GeneticVariation CLINVAR

dbSNP: rs63750219
rs63750219
PSEN1
A 0.700 GeneticVariation CLINVAR

dbSNP: rs747306346
rs747306346
SORL1
0.700 GeneticVariation UNIPROT

dbSNP: rs866101707
rs866101707
VCP
A 0.700 GeneticVariation CLINVAR

dbSNP: rs541458
rs541458 		0.760 GeneticVariation BEFREE <b>Background:</b> Phosphatidylinositol binding clathrin assembly protein (<i>PICALM</i>) rs541458 C allele has been identified and validated to be associated with a reduction of Alzheimer's disease (AD) risk. 31133980

2019
dbSNP: rs74315408
rs74315408
PRNP
0.010 GeneticVariation BEFREE <b>Background:</b> In this study, a known <i>PRNP</i> mutation, Val180Ile (c.G538A), was reported in a 58 years old female patient, clinically diagnosed with Alzheimer's disease (AD). 31410005

2019
dbSNP: rs9357347
rs9357347
LOC107986595
0.020 GeneticVariation BEFREE <b>Conclusion:</b> This study suggested that rs9357347 reduced the risk of AD by modulating both amyloid-β pathology and neuronal degeneration. 31379492

2019
dbSNP: rs671
rs671
ALDH2
0.020 GeneticVariation BEFREE <b>Conclusions:</b> In conclusion, our meta-analysis indicated that the <i>ALDH2</i> rs671 G>A polymorphism plays an important role in AD development. 30984100

2019
dbSNP: rs2333227
rs2333227
MPO
0.010 GeneticVariation BEFREE <i>MPO</i> rs2333227 polymorphism was positively associated with AD risk, especially under the AA+GA vs. GG and A vs. G genetic models (<i>P</i>=0.042, OR=1.719, 95%CI=1.017-2.906; <i>P</i>=0.041, OR=1.582, 95%CI=1.016-2.463). 29296208

2017
dbSNP: rs1217691063
rs1217691063
MTHFR
0.100 GeneticVariation BEFREE <i>MTHFR</i> C677T TT and CT genotypes had significant associations with AD risk in all ra</span>cial populations (RR = 1.13, <i>p</i> = 0.0047; and RR = 1.12, <i>p</i> < 0.0001 respectively). 28085050

2017