rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
To explore mechanisms that may underlie associations between Alzheimer's disease (AD) and schizophrenia risk CLU gene and verbal memory, one of the most affected cognitive domains in both conditions, we studied DNA methylation in a region between AD-associated SNPs rs9331888 and rs9331896 in 72 healthy individuals and 73 schizophrenia patients.
|
30599442 |
2019 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Our meta-analysis demonstrated that the rs9331888/C > G polymorphism in the clusterin gene might contribute to AD susceptibility especially in Caucasian populations.
|
28168383 |
2017 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The clusterin (CLU) locus was an independent genetic risk factor for MCI to AD progression (CLU rs9331888: hazard ratio (HR)=1.187 (1.054-1.32); P=0.0035).
|
26976043 |
2017 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Multivariate analysis might suggest that regular "mind-body" religious meditative activities may be negatively associated with AD in this population, as well as the CLU genotype at rs9331888.
|
26757186 |
2016 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
We observed significant association between rs9331888 polymorphism and AD in pooled populations (P = 2.26E - 07, odds ratio (OR) = 1.10, 95% confidence interval (CI) 1.06-1.14).
|
25633098 |
2016 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Our analysis demonstrated that CLU SNP r</span>s9331888</span> might be associated with an increased AD risk in Caucasian population, but not in Asian population.
|
25703218 |
2015 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
This study indicates that the rs9331888 AD-risk variant is associated with low blood clusterin levels.
|
22258514 |
2012 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
BEFREE |
These results suggest a biological mechanism for the genetic association of CLU with AD risk and indicate that rs9331888 is one of the functional DNA variants underlying this association.
|
21892414 |
2011 |
rs9331888
|
|
G |
0.880 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
rs9331888
|
|
|
0.880 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |