Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs759834365
rs759834365
0.050 GeneticVariation BEFREE To examine the influence of the brain-derived neurotrophic factor (<i>BDNF</i>) Val66Met polymorphism on longitudinal cognitive trajectories in a large, cognitively healthy cohort enriched for Alzheimer disease (AD) risk and to understand whether β-amyloid (Aβ) burden plays a moderating role in this relationship. 28468845

2017

dbSNP: rs759834365
rs759834365
0.050 GeneticVariation BEFREE While allelic variation in BDNF Val66Met may influence + related neurodegeneration and memory loss over the short term, this is not related to serum mBDNF. 28720165

2017

dbSNP: rs759834365
rs759834365
0.050 GeneticVariation BEFREE We aimed to determine the effect of BDNF Val66Met on cognitive function, hippocampal function, tau and amyloid-β in preclinical autosomal dominant Alzheimer's disease. 27521573

2016

dbSNP: rs759834365
rs759834365
0.050 GeneticVariation BEFREE Among + women, ε4 carriers reported greater anxiety symptoms than non-ε4 carriers (d = 0.83), and female BDNF rs6265 Val66 Met allele carriers reported greater depressive symptoms (d = 0.29). 27742526

2016

dbSNP: rs759834365
rs759834365
0.050 GeneticVariation BEFREE BDNF Val66Met did not relate to the amount of or to the rate of Aβ accumulation in either group. 23769397

2013