Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.080 | GeneticVariation | BEFREE | Higher reward value of starvation imagery in anorexia nervosa and association with the Val66Met BDNF polymorphism. | 27271855 | 2016 |
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0.080 | GeneticVariation | BEFREE | Our analyses indicate that the BDNF Val66Met variant is not associated with AN at detectable levels. | 21936709 | 2013 |
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0.080 | GeneticVariation | BEFREE | No difference was found in minimum BMIs related to Val66Met in AN (one-way ANOVA, P > 0.05). | 22127997 | 2012 |
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0.080 | GeneticVariation | BEFREE | BDNF has been involved in body weight regulation and its Val66Met polymorphism associated with AN. | 17197106 | 2007 |
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0.080 | GeneticVariation | BEFREE | Some studies have shown association of BDNF -270C/T single-nucleotide polymorphism (SNP) with bulimia nervosa (BN), while BDNF Val66Met variant has been shown to be associated with both BN and anorexia nervosa (AN). | 17376155 | 2007 |
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0.080 | GeneticVariation | BEFREE | Case-control studies also suggest a BDNF contribution in the aetiology of ED: we have previously reported a strong association between the Met66 variant within the BDNF gene, restricting AN (ANR) and minimum body mass index (minBMI) in a Spanish sample, and a positive association between the Val66Met and -270C/T BDNF SNPs and ED in six different European populations. | 15657604 | 2005 |
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0.080 | GeneticVariation | BEFREE | Additionally, we genotyped two common polymorphisms (rs6265: p.V66M; c.-46C > T) in 118 patients with anorexia nervosa, 80 patients with bulimia nervosa, 88 patients with ADHD, and 96 normal weight controls. | 15457498 | 2005 |
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0.080 | GeneticVariation | BEFREE | We previously reported a strong association of the Met66 allele of the Val66Met BDNF variant with restricting AN (ANR) and low minimum body mass index in Spanish patients. | 15115760 | 2004 |