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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The impact of BDNF Val66Met polymorphism on cognition in Bipolar Disorder: A review: Special Section on "Translational and Neuroscience Studies in Affective Disorders" Section Editor, Maria Nobile MD, PhD. This Section of JAD focuses on the relevance of translational and neuroscience studies in providing a better understanding of the neural basis of affective disorders. The main aim is to briefly summaries relevant research findings in clinical neuroscience with particular regards to specific innovative topics in mood and anxiety disorders.
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30078664 |
2019 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The aim of the present case-control study was to explore the association between BDNF Val66Met (rs6265) polymorphism and generalized anxiety disorder in Mexican individuals, and whether this polymorphism plays a role in the symptomatology of anxiety.A total of 212 subjects were included in the study.
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30882674 |
2019 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Interactive genetic association with anxiety was observed such that effects of 5-HTTLPR depended on the BDNF Val66Met polymorphism (rs6265 variant), with higher anxiety scores in short and Met carriers compared to the other allelic groups.
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30711709 |
2019 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
The BDNF Val66Met gene polymorphism is associated with increased alexithymic and anticipatory anxiety in patients with panic disorder.
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30269521 |
2019 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Effect of Early-Life Fluoxetine on Anxiety-Like Behaviors in BDNF Val66Met Mice.
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29084453 |
2017 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
On the contrary, BDNF met allele carriers showed a reduced acoustic startle response which reached significance in most samples (N1: p=0.004; N2: p=0.045; N3: n.s., N4: p=0.043) pointing to differential effects of BDNF val(66)met on distinct endophenotypes of anxiety and stress-related responses.
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26773399 |
2016 |
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rs759834365
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0.100 |
GeneticVariation |
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BDNF Val66Met, stress, and positive mothering: Differential susceptibility model of adolescent trait anxiety.
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26119141 |
2015 |
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rs759834365
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0.100 |
GeneticVariation |
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Here we comprehensively review the role and relevance of the Val66Met polymorphism in psychiatric disorders, with emphasis on suicidal behavior and anxiety, eating, mood and psychotic disorders.
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25824305 |
2015 |
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rs759834365
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0.100 |
GeneticVariation |
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Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes.
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25640836 |
2015 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Patients with depressive or anxiety disorders and with available BDNF Val(66)Met polymorphism data (N=1271) were selected from Netherlands Study of Depression and Anxiety (NESDA).
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25618300 |
2015 |
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rs759834365
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0.100 |
GeneticVariation |
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We aimed to explore whether anxiety in BD offspring was associated with the BDNF Val66Met polymorphism.64 BD offspring (mean age: 13.73 (S.D.
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25498133 |
2015 |
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rs759834365
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0.100 |
GeneticVariation |
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The Association of BDNF Val66Met Polymorphism With Trait Anxiety in Panic Disorder.
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26037856 |
2014 |
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rs759834365
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0.100 |
GeneticVariation |
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We therefore examined the association of the COMT Val158Met and BDNF Val66Met polymorphisms with BP-II with and without comorbidity of AD, and possible interactions between these genes.
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23026378 |
2013 |
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rs759834365
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0.100 |
GeneticVariation |
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In this work, we review the literature focused on the BDNF Val(66)Met polymorphism and anxiety, and discuss biological findings from animal models to clinical studies.
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24051499 |
2013 |
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rs759834365
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0.100 |
GeneticVariation |
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Because the Val/Val genotype of the BDNF Val66Met polymorphism, rather than the other two polymorphisms, has been associated with anxiety, it seems to affect BP-I comorbid with AD without the involvement of the DRD3 Seg9Gly polymorphism, but may modify the involvement of DRD3 Gly/Gly in BP-II comorbid with AD.
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24021960 |
2013 |
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rs759834365
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0.100 |
GeneticVariation |
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Gender-specific effects of brain-derived neurotrophic factor Val66Met polymorphism and childhood maltreatment on anxiety.
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23221871 |
2013 |
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rs759834365
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0.100 |
GeneticVariation |
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Gray matter volume in adolescent anxiety: an impact of the brain-derived neurotrophic factor Val(66)Met polymorphism?
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23357445 |
2013 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Our results support the a priori hypothesis of an association between anxiety and the polymorphism Val66Met.
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21839144 |
2011 |
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rs759834365
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0.100 |
GeneticVariation |
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In line with recent studies investigating the role of BDNF Val66Met and DRD2/ANKK1 Taq IA polymorphisms on anxiety and gray matter volume in the ACC, our findings provide the first evidence for a genetic contribution to alexithymia.
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21097659 |
2011 |
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rs759834365
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0.100 |
GeneticVariation |
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BDNF Val66Met polymorphism is associated with higher anticipatory cortisol stress response, anxiety, and alcohol consumption in healthy adults.
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21596481 |
2011 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
Recently, a single nucleotide polymorphism (SNP) in the BDNF gene (Val66Met) has been found to be associated with depression and anxiety disorders.
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20515664 |
2010 |
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rs759834365
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0.100 |
GeneticVariation |
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A common polymorphism of the brain-derived neurotrophic factor (BDNF) gene (Val66Met) has been implicated in anxiety, which is associated with lower vagal activity.
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20213725 |
2010 |
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rs759834365
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0.100 |
GeneticVariation |
BEFREE |
A polymorphism of the human Brain Derived Neurotrophic Factor (BDNF) gene that produces a valine-to-methionine substitution at codon 66 (Val66Met) is linked to adult anxiety and mood disorders, possibly through effects on brain circuitry function.
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19931400 |
2010 |
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rs759834365
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0.100 |
GeneticVariation |
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The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans.
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20478625 |
2010 |
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rs759834365
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0.100 |
GeneticVariation |
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Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety.
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19153574 |
2009 |