rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
Smoking confers a MTHFR 677C>T genotype-dependent risk for systemic atherosclerosis: results from a large number of elderly autopsy cases that died in a community-based general geriatric hospital.
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19403988 |
2009 |
rs1217691063
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|
|
0.100 |
GeneticVariation |
BEFREE |
This study aimed at assessing the effect of folic acid supplementation quantitatively in each MTHFR C677T genotype and considered the efficiency of tailor-made prevention of atherosclerosis.
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15895286 |
2005 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
We measured plasma high-sensitive C-reactive protein (hs-CRP) levels and screened for the C677T polymorphism of the 5-10 methylenetetrahydrofolate reductase gene (MTHFR), which is considered a genetic risk factor for atherosclerosis, by HinfI digestion.
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15764293 |
2005 |
rs1217691063
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|
|
0.100 |
GeneticVariation |
BEFREE |
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with reduced enzyme activity, hyperhomocysteinaemia and increased risk for atherosclerosis in homozygotes.
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11094304 |
2000 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
One putative determinant of PAD is the 677C>T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR), which has previously been found to associate with various diabetic complications including retinopathy, nephropathy, atherosclerosis and coronary heart disease.
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16274479 |
2005 |
rs1217691063
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|
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0.100 |
GeneticVariation |
BEFREE |
High plasma homocysteine, a risk factor for atherosclerosis, is frequently caused by a common mutation in the gene for the enzyme, 5,10-methylenetetrahydrofolate reductase (MTHFR), C677T (alanine to valine substitution) or low intake of B vitamins that affect the remethylation or transsulfuration pathways in homocysteine metabolism.
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12204804 |
2002 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
Relationships between IC- or EC atherosclerosis and plasma tHcyt level and/or MTHFR 677C>T genotypes were analyzed after adjusting for vascular risk factors.
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20825473 |
2011 |
rs1217691063
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|
|
0.100 |
GeneticVariation |
BEFREE |
The guanine to thymine polymorphism at position 894 of the eNOS gene (resulting in a change from glutamate to aspartate [Asp] at codon 298 [Asp298]) and the methylenetetrahydrofolate reductase (MTHFR) gene polymorphism (C677T) have been reported to be associated with atherosclerosis and cardiovascular disease.
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15494775 |
2004 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
Associations of methylenetetrahydrofolate reductase C677T polymorphism with markers of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.
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17934972 |
2008 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the frequency of C677T methylenetetrahydrofolate reductase (MTHFR) mutation in healthy Croatian volunteers and in patients with atherosclerosis.
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12927690 |
2003 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
Atherosclerosis in male patients with ankylosing spondylitis: the relation with methylenetetrahydrofolate reductase (C677T) gene polymorphism and plasma homocysteine levels.
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23247802 |
2013 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.
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19398669 |
2009 |
rs1217691063
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0.100 |
GeneticVariation |
BEFREE |
Hyperhomocysteinaemia, a risk factor for atherosclerosis, is common in dialysis patients and particularly in those homozygous for a common polymorphism in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene (C677T transition).
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11865092 |
2002 |
rs1217691063
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|
|
0.100 |
GeneticVariation |
BEFREE |
The association between plasma Hcy and serum IL-6 levels supports the hypothesis that the activation of innate immunity is involved in the pathogenesis of arteriosclerosis in patients with diabetes mellitus who are homozygous for the TT genotype of C677T MTHFR.
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15931619 |
2005 |