rs33980500
|
|
T |
0.820 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
rs33980500
|
|
|
0.820 |
GeneticVariation |
BEFREE |
However, the dominant PsA-associated TRAF3IP2 (Act1) gene single-nucleotide polymorphism (rs33980500) results in decreased binding of Act1 to TRAF6.
|
23116200 |
2012 |
rs33980500
|
|
T |
0.820 |
GeneticVariation |
GWASDB |
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
|
20953186 |
2010 |
rs33980500
|
|
T |
0.820 |
GeneticVariation |
GWASCAT |
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
|
20953186 |
2010 |
rs33980500
|
|
|
0.820 |
GeneticVariation |
BEFREE |
A stratified analysis of our datasets including only PsA cases (1,922 cases compared to 8,037 controls, P = 4.57 × 10⁻¹² for rs33980500) suggested that TRAF3IP2 represents a shared susceptibility for PsV and PsA.
|
20953188 |
2010 |
rs13017599
|
|
G |
0.810 |
GeneticVariation |
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
rs13017599
|
|
|
0.810 |
GeneticVariation |
GWASDB |
However, conditional analysis indicated that rs13017599, rather than rs702873, accounts for the PsA association at REL.
|
22170493 |
2012 |
rs13017599
|
|
|
0.810 |
GeneticVariation |
GWASCAT |
However, conditional analysis indicated that rs13017599, rather than rs702873, accounts for the PsA association at REL.
|
22170493 |
2012 |
rs13017599
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Significant evidence for association with susceptibility to PsA was found toa SNP mapping to the REL (rs13017599, p(trend)=5.2×10(4)) gene, while nominal evidence for association (p(trend)<0.05) was found to seven other loci including PLCL2 (rs4535211, p=1.7×10(-3)); STAT4 (rs10181656, p=3.0×10(-3)) and the AFF3, CD28, CCL21, IL2 and KIF5A loci.
|
22328738 |
2012 |
rs702873
|
|
|
0.810 |
GeneticVariation |
GWASCAT |
However, conditional analysis indicated that rs13017599, rather than rs702873, accounts for the PsA association at REL.
|
22170493 |
2012 |
rs702873
|
|
|
0.810 |
GeneticVariation |
BEFREE |
However, conditional analysis indicated that rs13017599, rather than rs702873, accounts for the PsA association at REL.
|
22170493 |
2012 |
rs702873
|
|
|
0.810 |
GeneticVariation |
GWASDB |
However, conditional analysis indicated that rs13017599, rather than rs702873, accounts for the PsA association at REL.
|
22170493 |
2012 |
rs12188300
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
|
20953186 |
2010 |
rs12188300
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
|
20953186 |
2010 |
rs13191343
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
|
20953186 |
2010 |
rs13191343
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
|
20953186 |
2010 |
rs13190932
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.
|
30552173 |
2019 |
rs12044149
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
Among identified psoriasis risk variants, three were more strongly associated with PsC than PsA (rs12189871 near HLA-C, p = 5.0 × 10(-19); rs4908742 near TNFRSF9, p = 0.00020; rs10888503 near LCE3A, p = 0.0014), and two were more strongly associated with PsA than PsC (rs12044149 near IL23R, p = 0.00018; rs9321623 near TNFAIP3, p = 0.00022).
|
26626624 |
2015 |
rs12044149
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Among identified psoriasis risk variants, three were more strongly associated with PsC than PsA (rs12189871 near HLA-C, p = 5.0 × 10(-19); rs4908742 near TNFRSF9, p = 0.00020; rs10888503 near LCE3A, p = 0.0014), and two were more strongly associated with PsA than PsC (rs12044149 near IL23R, p = 0.00018; rs9321623 near TNFAIP3, p = 0.00022).
|
26626624 |
2015 |
rs13190932
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We replicated PsA associations at HLA-C and IL12B and identified a new association at TRAF3IP2 (rs13190932, P = 8.56 × 10⁻¹⁷).
|
20953186 |
2010 |
rs10865331
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.
|
30552173 |
2019 |
rs114212579
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.
|
30552173 |
2019 |
rs114265779
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.
|
30552173 |
2019 |
rs114383947
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.
|
30552173 |
2019 |
rs114598684
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.
|
30552173 |
2019 |