|
rs2476601
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs2004640
|
|
T |
0.790 |
CausalMutation |
CLINVAR |
|
|
|
|
rs3087456
|
|
G |
0.780 |
SusceptibilityMutation |
CLINVAR |
|
|
|
|
rs2240340
|
|
C |
0.770 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1057523354
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1557787212
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1566328963
|
|
A |
0.700 |
SusceptibilityMutation |
CLINVAR |
|
|
|
|
rs3766379
|
|
C |
0.700 |
SusceptibilityMutation |
CLINVAR |
|
|
|
|
rs1801133
|
|
|
0.050 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Our results showed that the MTHFR [677C>T (rs1801133)] TT genotype is associated with ADRs to MTX in Chinese RA patients.
|
30546311 |
2018 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Our results showed that the MTHFR [677C>T (rs1801133)] TT genotype is associated with ADRs to MTX in Chinese RA patients.
|
30546311 |
2018 |
|
rs2910164
|
|
|
0.100 |
GeneticVariation |
BEFREE |
<b>Conclusions:</b> The association of miR-146a rs2910164 (G/C) with RA was not found.
|
31235484 |
2019 |
|
rs2910164
|
|
|
0.100 |
GeneticVariation |
BEFREE |
<b>Significance:</b> The miR-146a rs2910164 G > C polymorphism was not associated with susceptibility to RA.
|
30498453 |
2018 |
|
rs2476601
|
|
|
1.000 |
GeneticVariation |
BEFREE |
167 patients with RA and 177 healthy controls are genotyped by polymerase chain reaction (PCR)-RFLP for the SNP (rs2476601, A/G) of PTPN22 gene.
|
19357851 |
2009 |
|
rs11761528
|
|
|
0.010 |
GeneticVariation |
BEFREE |
448 RA and 648 healthy controls were genotyped for single-nucleotide polymorphisms (SNPs) in genes ZKSCAN5 (rs11761528), SULT2A1 (rs2637125), HHEX (rs2497306), and ARPC1A (rs740160).
|
28712091 |
2018 |
|
rs740160
|
|
|
0.010 |
GeneticVariation |
BEFREE |
448 RA and 648 healthy controls were genotyped for single-nucleotide polymorphisms (SNPs) in genes ZKSCAN5 (rs11761528), SULT2A1 (rs2637125), HHEX (rs2497306), and ARPC1A (rs740160).
|
28712091 |
2018 |
|
rs121912656
|
|
|
0.010 |
GeneticVariation |
BEFREE |
G245D mutation might especially need further study as it is the first recurrently identified p53 mutation in RA and is also one of the frequently identified mutations in human cancers.
|
10788533 |
2000 |
|
rs1799945
|
|
|
0.020 |
GeneticVariation |
BEFREE |
H63D mutation appears to play a role in pathogenesis of RA.
|
10990216 |
2000 |
|
rs1799945
|
|
|
0.020 |
GeneticVariation |
BEFREE |
H63D mutation may play a role in the pathogenesis of rheumatoid arthritis.
|
15785438 |
2004 |
|
rs2476601
|
|
|
1.000 |
GeneticVariation |
BEFREE |
Additional analyses identified two SNPs on a single common haplotype that are associated with RA independent of R620W, suggesting that R620W and at least one additional variant in the PTPN22 gene region influence RA susceptibility.
|
16175503 |
2005 |
|
rs3736228
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A1330V polymorphism of low-density lipoprotein receptor-related protein 5 gene and self-reported incident fractures in Japanese female patients with rheumatoid arthritis.
|
19023643 |
2009 |
|
rs2903692
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs2903692 conferred a protective effect on patients with T1D, MS and RA.
|
19221398 |
2010 |
|
rs61752717
|
|
|
0.010 |
GeneticVariation |
BEFREE |
M694V was the only variant that was significantly more common in the AS group than in the combined or individual control groups (P = 0.026 for AS patients versus healthy controls, P = 0.046 for AS patients versus RA patient controls, and P = 0.008 for AS patients versus healthy and RA patient control groups).
|
20533539 |
2010 |
|
rs6908425
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs6908425 T>C in CDKAL1 was significantly different between SAPHO cases and healthy controls (odds ratios = 2.056, 95% confidence intervals: 1.211-3.490; p = 0.007), but no SNPs were associated with the risk of developing RA, AS, or SPA (p > 0.05).
|
27936930 |
2017 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
C677T MTHFR gene polymorphism is associated with RA in Egyptians.
|
28215593 |
2017 |
|
rs2476601
|
|
|
1.000 |
GeneticVariation |
BEFREE |
A C1858T single nucleotide polymorphism within PTPN22 (which encodes PTPN22<sup>R620W</sup>) is associated with an enhanced susceptibility to multiple autoimmune diseases including type 1 diabetes and rheumatoid arthritis.
|
30139951 |
2018 |