Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10919563
rs10919563
PTPRC
0.740 GeneticVariation BEFREE The most significant result was obtained with rs10919563 in PTPRC, which is a confirmed RA susceptibility locus. 25896535

2016
dbSNP: rs10919563
rs10919563
PTPRC
0.740 GeneticVariation BEFREE The PTPRC rs10919563 A allele shows a poor response to anti-TNF therapy, and the FCGR2A HH + HR genotype shows a poor response to adalimumab for RA. 27074847

2016
dbSNP: rs10919563
rs10919563
PTPRC
0.740 GeneticVariation BEFREE Presence of the rs10919563 RA susceptibility variant at the PTPRC gene locus predicts improved response to anti-TNF biologic therapy. 21952740

2012
dbSNP: rs10919563
rs10919563
PTPRC
0.740 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
dbSNP: rs10919563
rs10919563
PTPRC
0.740 GeneticVariation BEFREE Of the 31 RA-associated risk alleles, a SNP at the PTPRC (also known as CD45) gene locus (rs10919563) was associated with the primary end point, a EULAR good response versus no response (odds ratio [OR] 0.55, P = 0.0001 in the multivariate model). 20309874

2010