| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.770 | GeneticVariation | BEFREE | This work supports the association of the T allele of PADI4 rs2240340 with RA in Asians. | 28653215 | 2017 |
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|
0.770 | GeneticVariation | BEFREE | Failure to replicate the association of PADI4(rs2240340)/(PADI4_94) in Egyptian RA patients provides further support for the notion that genetic architecture of RA is different in multiple populations of European, Asian, African, and Middle Eastern ancestries. | 27125674 | 2016 |
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|
0.770 | GeneticVariation | BEFREE | RA risk genotypes of PADI4 were specifically associated with anti-CCP positive RA (rs2240340: p=5.13×10⁻⁶; rs1748033: p=2.97×10⁻³, respectively). | 24564960 | 2014 |
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|
0.770 | GeneticVariation | BEFREE | These findings suggest that the functional single-nucleotide polymorphism PADI4 rs2240340 G/A variant allele is associated with RA development, especially among older patients and ACPA-positive patients. | 22505706 | 2012 |
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|
0.770 | GeneticVariation | BEFREE | The PADI4_94 (rs2240340) single nucleotide polymorphism (SNP) was directly genotyped in a cohort of unrelated UK Caucasian patients with RA (n=3732) and population controls (n=3039). | 19470526 | 2010 |
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|
0.770 | GeneticVariation | BEFREE | We studied RA risk associated with PTPN22 (rs2476601), PADI-4 (rs2240340), and CTLA-4 (rs3087243) in the Nurses' Health Study (NHS) and NHSII. | 18462498 | 2008 |
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|
0.770 | GeneticVariation | BEFREE | Only the SNP rs2240340/padi4_94 was modestly associated with RA [allele odds ratio (OR) 1.22, 95% confidence interval (CI) 1.04-1.43, P=0.012]. | 18087673 | 2008 |
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|
C | 0.770 | GeneticVariation | CLINVAR |