Gene: HLA-DRB1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs660895
rs660895
HLA-DRB1
0.810 GeneticVariation BEFREE The HLA-DRB1 rs660895 showed both wild (AA) and heterozygote (AG) genotype but the heterozygote allele was found to be associated with reduced risk of RA compared to controls [OR = 0.531, p = .024]. 29168332

2018
dbSNP: rs660895
rs660895
HLA-DRB1
0.810 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
dbSNP: rs660895
rs660895
HLA-DRB1
G 0.810 GeneticVariation GWASCAT High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
dbSNP: rs660895
rs660895
HLA-DRB1
0.810 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761

2011
dbSNP: rs660895
rs660895
HLA-DRB1
0.810 GeneticVariation GWASDB TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. 17804836

2007
dbSNP: rs660895
rs660895
HLA-DRB1
0.810 GeneticVariation GWASCAT TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. 17804836

2007
dbSNP: rs615672
rs615672
HLA-DRB1
0.800 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761

2011
dbSNP: rs615672
rs615672
HLA-DRB1
0.800 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007
dbSNP: rs615672
rs615672
HLA-DRB1
0.800 GeneticVariation GWASDB Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007
dbSNP: rs2516049
rs2516049
HLA-DRB1
0.700 GeneticVariation GWASDB Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis--a genome-wide study combined with immunological analyses. 21673997

2011
dbSNP: rs2516049
rs2516049
HLA-DRB1
0.700 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761

2011
dbSNP: rs9270657
rs9270657
HLA-DRB1
0.700 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761

2011
dbSNP: rs2516049
rs2516049
HLA-DRB1
0.700 GeneticVariation GWASDB REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088

2009
dbSNP: rs2516049
rs2516049
HLA-DRB1
0.700 GeneticVariation GWASDB TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. 17804836

2007
dbSNP: rs17879469
rs17879469
HLA-DRB1
0.020 GeneticVariation BEFREE Cytotoxic T-lymphocyte antigen 4 (CTLA4) polymorphisms located in the promotor region at positions -318 (C/T) and in exon 1 (49 A/ G) were investigated in 138 Spanish patients (37 men and 101 women) with rheumatoid arthritis and in 305 ethnically-matched healthy controls. 10203024

1999
dbSNP: rs17879469
rs17879469
HLA-DRB1
0.020 GeneticVariation BEFREE We have studied the distribution of the CTLA4 exon 1 polymorphism (49 A/G) in rheumatoid arthritis. 9459504

1998
dbSNP: rs771131230
rs771131230
HLA-DRB1
0.010 GeneticVariation BEFREE Japanese patients with SLE (n=716), those with rheumatoid arthritis (RA) (n=327), and healthy control subjects (n=351) were genotyped for the Val129 Met polymorphism (rs1051792) and transmembrane (TM) alanine-encoding GCT repeats, termed A4, A5, A5.1, A6, and A9, in the MICA gene. 21702010

2011
dbSNP: rs773389640
rs773389640
HLA-DRB1
0.010 GeneticVariation BEFREE Japanese patients with SLE (n=716), those with rheumatoid arthritis (RA) (n=327), and healthy control subjects (n=351) were genotyped for the Val129 Met polymorphism (rs1051792) and transmembrane (TM) alanine-encoding GCT repeats, termed A4, A5, A5.1, A6, and A9, in the MICA gene. 21702010

2011