rs1342326
|
|
|
0.840 |
GeneticVariation |
BEFREE |
C/C genotype of rs1342326 [OR (95% CI) 2.50 (1.33-4.69)] and A/A genotype of rs3939286 [OR (95% CI) 2.18 (1.05-4.52)] were associated with higher risk of asthma development.
|
31820077 |
2020 |
rs1342326
|
|
|
0.840 |
GeneticVariation |
BEFREE |
The presence of rs1342326 polymorphism was significantly associated with a lower risk of asthma development.
|
28985997 |
2018 |
rs1342326
|
|
|
0.840 |
GeneticVariation |
BEFREE |
The level of IL33 was significantly higher in asthma and MS patients compared to the control group (P< 0.001- P<0.001).The frequency distribution of the genotype in rs1342326 variant of IL-33 gene in patients with asthma, MS and healthy subjects was not significantly different (P>0.05).
|
30950351 |
2019 |
rs1342326
|
|
|
0.840 |
GeneticVariation |
GWASDB |
Genome-wide association study to identify genetic determinants of severe asthma.
|
22561531 |
2012 |
rs1342326
|
|
C |
0.840 |
GeneticVariation |
GWASDB |
We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).
|
20860503 |
2010 |
rs1342326
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).
|
20860503 |
2010 |
rs1342326
|
|
|
0.840 |
GeneticVariation |
BEFREE |
We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).
|
20860503 |
2010 |
rs1342326
|
|
|
0.840 |
GeneticVariation |
GWASDB |
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.
|
21907864 |
2011 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Two SNPs in TSLP (rs1837253 and rs2289276) were significantly associated with a reduced risk of asthma in combined analyses of all cohorts (P values of 2 × 10(-5) and 1 × 10(-5) , respectively).
|
20560908 |
2010 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
GWASCAT |
Identification of Four Novel Loci in Asthma in European American and African American Populations.
|
27611488 |
2017 |
rs1837253
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
|
24388013 |
2014 |
rs1837253
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
|
31619474 |
2019 |
rs1837253
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.
|
30552067 |
2019 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
GWASCAT |
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
|
21804549 |
2011 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
BEFREE |
rs1837253 is associated with asthma susceptibility and may increase the risk of asthma in Zhuang people in Guangxi.
|
31066119 |
2019 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
GWASDB |
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
|
21804549 |
2011 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Surprisingly, rs1837253 (consistently associated with asthma) showed no correlation with TSLP expression levels.
|
26119467 |
2015 |
rs1837253
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
|
30929738 |
2019 |
rs1837253
|
|
C |
0.840 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
|
21804548 |
2011 |
rs1837253
|
|
C |
0.840 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
|
21804548 |
2011 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
GWASCAT |
A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.
|
29785011 |
2018 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
GWASDB |
A large-scale, consortium-based genomewide association study of asthma.
|
20860503 |
2010 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
GWASCAT |
Detection and interpretation of shared genetic influences on 42 human traits.
|
27182965 |
2016 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Recent candidate gene and genome-wide association studies have identified "protective" associations between the single-nucleotide polymorphism (SNP) rs1837253 in the TSLP gene and risk for allergy, asthma, and airway hyperresponsiveness.
|
25515628 |
2015 |
rs7927894
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Subgroup analysis revealed no significant association of rs7927894 with early age of onset of the disease, concomitant asthma and allergic rhinoconjunctivitis, total serum IgE levels and family history of atopy.
|
23557745 |
2013 |