Source: ALL
Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASDB Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548

2011

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation BEFREE Surprisingly, rs1837253 (consistently associated with asthma) showed no correlation with TSLP expression levels. 26119467

2016

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548

2011

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2017

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503

2010

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASCAT Identification of Four Novel Loci in Asthma in European American and African American Populations. 27611488

2017

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation BEFREE In a sex-stratified analysis, the T allele of rs1837253 was significantly associated with a reduced risk of asthma in males only (P = 3 × 10(-6) ). 20560908

2011

dbSNP: rs1837253
rs1837253
0.820 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013

2014

dbSNP: rs1342326
rs1342326
0.810 GeneticVariation BEFREE We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503

2010

dbSNP: rs1342326
rs1342326
0.810 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864

2011

dbSNP: rs1342326
rs1342326
0.810 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503

2010

dbSNP: rs1342326
rs1342326
0.810 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531

2012

dbSNP: rs1342326
rs1342326
0.810 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503

2010

dbSNP: rs7130588
rs7130588
0.810 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864

2011

dbSNP: rs7130588
rs7130588
0.810 GeneticVariation GWASCAT Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864

2011

dbSNP: rs7130588
rs7130588
0.810 GeneticVariation BEFREE Two loci were confirmed to associate with asthma risk in the replication cohorts and reached genome-wide significance in the combined analysis of all available studies (n=57,800): rs4129267 (OR 1·09, combined p=2·4×10(-8)) in the interleukin-6 receptor (IL6R) gene and rs7130588 (OR 1·09, p=1·8×10(-8)) on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32, also known as GARP). 21907864

2011

dbSNP: rs9268516
rs9268516
0.810 GeneticVariation BEFREE We also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus. 23028483

2013

dbSNP: rs9268516
rs9268516
0.810 GeneticVariation GWASDB Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. 23028483

2013

dbSNP: rs9268516
rs9268516
0.810 GeneticVariation GWASCAT Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. 23028483

2013

dbSNP: rs992969
rs992969
0.810 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503

2010

dbSNP: rs992969
rs992969
0.810 GeneticVariation BEFREE For ORMDL3-GSDMB region, rs8067378 (G allele protective against asthma) was correlated with decreased expression of GSDMB in BEC and BAL (P = 1.3 × 10(-4) and 0.04) but not ORMDL3. rs992969 in the promoter region of IL33 (A allele associated with higher eosinophil counts and risk for asthma) was correlated with increased expression of IL33 in BEC (P = 1.3 × 10(-6) ) but not in BAL. 26119467

2016

dbSNP: rs992969
rs992969
0.810 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018

dbSNP: rs10508372
rs10508372
0.800 GeneticVariation GWASDB Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548

2011