Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3771180
rs3771180
IL18R1 ; IL1RL1
0.820 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs3859192
rs3859192
GSDMA
0.820 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503

2010
dbSNP: rs4129267
rs4129267
IL6R
T 0.820 GeneticVariation GWASDB Two loci were confirmed to associate with asthma risk in the replication cohorts and reached genome-wide significance in the combined analysis of all available studies (n=57,800): rs4129267 (OR 1·09, combined p=2·4×10(-8)) in the interleukin-6 receptor (IL6R) gene and rs7130588 (OR 1·09, p=1·8×10(-8)) on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32, also known as GARP). 21907864

2011
dbSNP: rs7212938
rs7212938
GSDMA
0.820 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs7927894
rs7927894 		0.820 GeneticVariation GWASDB Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. 21150878

2011
dbSNP: rs10197862
rs10197862
IL18R1 ; IL1RL1
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs13408661
rs13408661
IL18R1 ; IL1RL1
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs13408661
rs13408661
IL18R1 ; IL1RL1
G 0.810 GeneticVariation GWASDB We also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus. 23028483

2012
dbSNP: rs2284033
rs2284033
IL2RB
0.810 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531

2012
dbSNP: rs2284033
rs2284033
IL2RB
G 0.810 GeneticVariation GWASDB We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503

2010
dbSNP: rs2284033
rs2284033
IL2RB
0.810 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864

2011
dbSNP: rs2786098
rs2786098
CRB1
0.810 GeneticVariation GWASDB We observed replication of the association of asthma with SNP rs2786098 in the independent series of persons of European ancestry (combined P=9.3x10(-11)). 20032318

2010
dbSNP: rs3117098
rs3117098
HCG23 ; TSBP1-AS1
G 0.810 GeneticVariation GWASDB Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548

2011
dbSNP: rs3771166
rs3771166
IL18R1
0.810 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531

2012
dbSNP: rs3771166
rs3771166
IL18R1
G 0.810 GeneticVariation GWASDB We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503

2010
dbSNP: rs3771166
rs3771166
IL18R1
0.810 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864

2011
dbSNP: rs3894194
rs3894194
GSDMA
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs3894194
rs3894194
GSDMA
A 0.810 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503

2010
dbSNP: rs3894194
rs3894194
GSDMA
0.810 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531

2012
dbSNP: rs3894194
rs3894194
GSDMA
0.810 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864

2011
dbSNP: rs404860
rs404860
NOTCH4
A 0.810 GeneticVariation GWASDB We observed the most significant association with adult asthma at rs404860 in the major histocompatiblity complex region (P = 4.07 × 10(-23)), which is close to rs2070600, a SNP previously reported for association with FEV(1)/FVC in genome-wide association studies for lung function. 21804548

2011
dbSNP: rs4794820
rs4794820
LRRC3C
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs4794820
rs4794820
LRRC3C
0.810 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531

2012
dbSNP: rs6503525
rs6503525
LRRC3C
C 0.810 GeneticVariation GWASDB Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. 21150878

2011
dbSNP: rs6503525
rs6503525
LRRC3C
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011