|
rs1042714
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Asthmatics heterozygous for Gln/Glu27 had significantly later asthma onsets than those homozygous for Gln27.
|
10524541 |
1999 |
|
rs79908535
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A novel variant of human IL-13, Gln110Arg, on chromosome 5q31, associated with asthma rather than IgE levels in case-control populations from Britain and Japan [peak odds ratio (OR) = 2.31, 95% CI 1.33-4.00]; the variant also predicted asthma and higher serum IL-13 levels in a general, Japanese paediatric population.
|
10699178 |
2000 |
|
rs1051931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma.
|
10733466 |
2000 |
|
rs1320896171
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma.
|
10733466 |
2000 |
|
rs1805018
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma.
|
10733466 |
2000 |
|
rs4523
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene.
|
10830912 |
2000 |
|
rs1042713
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Neither the Arg16Gly nor Gln27Glu polymorphisms showed evidence of linkage to qualitative measures of asthma and bronchial hyperresponsiveness (BHR) (p > 0.10) or to quantitative measures of serum IgE and airway reactivity (p > 0.10).
|
10934093 |
2000 |
|
rs1042714
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Neither the Arg16Gly nor Gln27Glu polymorphisms showed evidence of linkage to qualitative measures of asthma and bronchial hyperresponsiveness (BHR) (p > 0.10) or to quantitative measures of serum IgE and airway reactivity (p > 0.10).
|
10934093 |
2000 |
|
rs10800812
|
|
T |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs1229598
|
|
C |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs17064520
|
|
C |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs2153101
|
|
T |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs2538026
|
|
T |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs4436440
|
|
T |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs4950929
|
|
A |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs545854
|
|
G |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs946263
|
|
A |
0.700 |
GeneticVariation |
GWASDB |
A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
|
11022011 |
2000 |
|
rs1538660
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a strong allelic association between BA in childhood and two of the SNP sites, T3214A (Cys1072Ser) and C3473T (Pro1158Leu); P = 0.000004 for T3214A and P = 0.0009 for C3473T.
|
11281413 |
2001 |
|
rs3204145
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a strong allelic association between BA in childhood and two of the SNP sites, T3214A (Cys1072Ser) and C3473T (Pro1158Leu); P = 0.000004 for T3214A and P = 0.0009 for C3473T.
|
11281413 |
2001 |
|
rs4987053
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, a significant association between asthma and CCR3 T51C polymorphism localized on chromosome 3p21 was found.
|
11307756 |
2001 |
|
rs1042713
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent studies have suggested that two polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) gene at codons 16 (arginine to glycine) and 27 (glutamine to glutamate) affect an individual's airway responsiveness, or response to acute or chronic beta(2)-agonist therapy but are not risk factors for asthma.
|
11371409 |
2001 |
|
rs1042714
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent studies have suggested that two polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) gene at codons 16 (arginine to glycine) and 27 (glutamine to glutamate) affect an individual's airway responsiveness, or response to acute or chronic beta(2)-agonist therapy but are not risk factors for asthma.
|
11371409 |
2001 |
|
rs1805014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The central objective of this study was to elucidate the role of the Ser786Pro polymorphism in asthma and its impact on IL-4R function.
|
11513543 |
2001 |
|
rs76863441
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Although lack of PAFAH activity is thought to be a risk factor for asthma, there are conflicting findings concerning association between the Val279Phe variant and asthma.
|
11916011 |
2002 |
|
rs4523
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The T924C polymorphism in the TBXA2R gene was recently found to be associated with asthma in Japanese adults but not in children.
|
12000493 |
2002 |