rs7216389
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Asthma susceptibility was associated with GG of the GSDMA (rs7212938) and TT of GSDMB (rs7216389).
|
21337730 |
2011 |
rs9910408
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Asthma treatment outcome in adults is associated with rs9910408 in TBX21 gene.
|
24107858 |
2013 |
rs3204145
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a strong allelic association between BA in childhood and two of the SNP sites, T3214A (Cys1072Ser) and C3473T (Pro1158Leu); P = 0.000004 for T3214A and P = 0.0009 for C3473T.
|
11281413 |
2001 |
rs5498
|
|
|
0.030 |
GeneticVariation |
BEFREE |
K469E showed association with asthma (P = 0.0037 with Armitage's trend test).
|
16625213 |
2006 |
rs555743307
|
|
|
0.090 |
GeneticVariation |
BEFREE |
I50V variants were not significantly associated with asthma.
|
17586032 |
2007 |
rs7216389
|
|
|
0.900 |
GeneticVariation |
BEFREE |
rs7216389 was significantly associated with the development of wheeze (hazard ratio 1.64 [1.05-2.59], P value = 0.03), asthma (hazard ratio, 1.88 [1.15-3.07], P = 0.01), and acute severe exacerbations (hazard ratio 2.66 [1.58-4.48], P value = 0.0002).
|
19029000 |
2009 |
rs200039720
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A53T heterozygotes had a two-fold increased risk for asthma in the Copenhagen City Heart Study and Copenhagen General Population Study combined (adjusted odds ratio 2.2(1.0-4.9)).
|
19910179 |
2010 |
rs1799983
|
|
|
0.060 |
GeneticVariation |
BEFREE |
G894T and -786T/C polymorphisms were not associated with asthma susceptibility.
|
22966886 |
2012 |
rs2243250
|
|
|
0.060 |
GeneticVariation |
BEFREE |
rs2243250 and rs2227284 are significantly associated with asthma and allergic rhinitis.
|
23654077 |
2013 |
rs4795405
|
|
|
0.720 |
GeneticVariation |
BEFREE |
rs4795405 was strongly associated with asthma without rhinitis, a subtype of asthma for which a higher degree of airway obstruction was found.
|
23964555 |
2013 |
rs1042714
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Gln/Glu27 polymorphism might be a contributor to asthma susceptibility for adults.
|
24992184 |
2014 |
rs11976862
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs11976862 homozygote mutant genotype GG was nominally associated with increased asthma risk (OR = 2.435, 95% CI: 1.221-4.854, p = 0.01148, p(corr) = 0.0127).
|
27133712 |
2016 |
rs12603332
|
|
|
0.730 |
GeneticVariation |
BEFREE |
rs12603332 is associated with male asthma patients specifically in urban areas of Lahore, Pakistan.
|
28055272 |
2017 |
rs721917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Met11Thr variation strongly affected serum SP-D levels and the degree of multimerization, but was not associated with COPD and asthma in the study.
|
28960651 |
2018 |
rs1837253
|
|
|
0.840 |
GeneticVariation |
BEFREE |
rs1837253 is associated with asthma susceptibility and may increase the risk of asthma in Zhuang people in Guangxi.
|
31066119 |
2019 |
rs3117098
|
|
|
0.810 |
GeneticVariation |
BEFREE |
rs3117098 may be the risk factor for asthma in Chinese Zhuang population.
|
31605414 |
2020 |
rs6967330
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A <i>CDHR3</i> SNP (rs6967330) with G to A base change has been linked to severe exacerbations of asthma and increased susceptibility to RV-C infections in young children.
|
30916989 |
2019 |
rs2233407
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A -673A>T (rs2233407) was associated with asthma development in subjects with atopic asthma (odds ratio = 0.56, p = 0.004).
|
20674643 |
2010 |
rs324011
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A case-control study for association of STAT6 polymorphisms rs4559 and rs324011 with asthma risk was performed.
|
30511616 |
2018 |
rs4559
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control study for association of STAT6 polymorphisms rs4559 and rs324011 with asthma risk was performed.
|
30511616 |
2018 |
rs11558538
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A common functional single nucleotide polymorphism (SNP) within the HNMT gene (C314T) was recently related to asthma.
|
15693910 |
2005 |
rs366510
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A five-SNP window between markers rs10402876 and rs366510 provided strongest evidence for linkage in the presence of linkage disequilibrium for asthma, high log[total IgE], and high log[IL-13]/[log[IFN-gamma] in terms of global P-values (P = 0.00027, 0.00013, and 0.003, respectively).
|
16355111 |
2006 |
rs2243250
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A four-way gene-gene interaction model consisting of IL13 rs20541, IL4 rs2243250</span>, ADRB2 rs1042713, and FCER1B rs569108 was chosen as the optimal one for determining asthma susceptibility (testing balanced accuracy = 0.6089, cross-validation consistency = 10/10, P = 6.98E-05).
|
26613553 |
2016 |
rs1042713
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A four-way gene-gene interaction model consisting of IL13 rs20541, IL4 rs2243250, ADRB2 rs1042713, and FCER1B rs569108 was chosen as the optimal one for determining asthma susceptibility (testing balanced accuracy = 0.6089, cross-validation consistency = 10/10, P = 6.98E-05).
|
26613553 |
2016 |
rs11252394
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study of bronchodilator response in asthmatics.
|
23508266 |
2014 |