| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | BEFREE | TLR4 Asp299Gly polymorphisms were associated with asthma and with decreased odds of nonatopic asthma compared with atopic asthma in the adult population in Crimea. | 31530336 | 2020 |
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0.080 | GeneticVariation | BEFREE | Our results indicated that the genotype and allele frequencies of the TLR2 Arg753Gln and TLR4 Asp299Gly polymorphisms were not significantly different between control subjects and asthm</span>atics and were not related to in asthma features such as IgE levels, asthma history and pulmonary factors. | 25530138 | 2015 |
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|
0.080 | GeneticVariation | BEFREE | Association of TLR4 (896A/G and 1196C/T) Gene Polymorphisms with Asthma Risk: A Meta-Analysis. | 26588249 | 2015 |
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|
0.080 | GeneticVariation | BEFREE | We aimed to investigate the effects of genetic variants of CD14 (-) and TLR4 (Asp299Gly, Thr399Ile) genes on asthma phenotypes in adults with asthma. | 24524443 | 2014 |
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|
0.080 | GeneticVariation | BEFREE | This is the first study conducted in India conferring TLR4 (Thr399Ile) polymorphism resistance towards asthma, while lack of association was found between TLR4 (Asp299Gly) polymorphism and asthma in the studied North Indian population. | 25331070 | 2014 |
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|
0.080 | GeneticVariation | BEFREE | Association between the TLR4 +896A>G (Asp299Gly) polymorphism and asthma: a systematic review and meta-analysis. | 23574398 | 2012 |
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|
0.080 | GeneticVariation | BEFREE | Determination of the TLR4 Asp299Gly/Thr399Ile haplotype is of no clinical benefit in predicting the nature or intensity of cytokine production in children whether currently healthy or among specific at-risk groups characterized by prior infantile broncholitis or current asthma. | 20711470 | 2010 |
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|
0.080 | GeneticVariation | BEFREE | The TLR4 (Asp299Gly) polymorphism was associated with a 4-fold higher prevalence of asthma in school-aged children (adjusted odds ratio 4.5, 95% CI 1.1-17.4) but not to allergic rhinoconjunctivitis. | 15356557 | 2004 |