Gene: ICAM1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5498
rs5498
ICAM1 ; ICAM4
0.030 GeneticVariation BEFREE The risk of asthma was higher for children carrying the rs5491 AT or TT genotypes and the rs5498 GG genotype (odds ratio = 1.68, 95% confidence interval 1.09–2.59) than for those with the rs5491 AA and rs5498 AA or AG genotypes (the reference group). 25003170

2014
dbSNP: rs5498
rs5498
ICAM1 ; ICAM4
0.030 GeneticVariation BEFREE The ICAM1 rs5498 A allele was positively associated with asthma development (p = 0.02) and ICAM1 gene expression (p = 0.01). 24393359

2014
dbSNP: rs5498
rs5498
ICAM1 ; ICAM4
0.030 GeneticVariation BEFREE K469E showed association with asthma (P = 0.0037 with Armitage's trend test). 16625213

2006
dbSNP: rs5491
rs5491
ICAM1
0.020 GeneticVariation BEFREE The risk of asthma was higher for children carrying the rs5491 AT or TT genotypes and the rs5498 GG genotype (odds ratio = 1.68, 95% confidence interval 1.09–2.59) than for those with the rs5491 AA and rs5498 AA or AG genotypes (the reference group). 25003170

2014
dbSNP: rs5491
rs5491
ICAM1
0.020 GeneticVariation BEFREE The following polymorphisms in ICAM1 were genotyped on 352 children with asthma and 270 controls: rs5491 (resulting in the amino-acid exchange K56M), rs5493 (G241S), rs5498 (K469E), rs5030400 (R478W) and rs885743 in the 3'-untranslated region. 16625213

2006