Gene: TNF ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800629
rs1800629
TNF
0.030 GeneticVariation BEFREE GSTP1 rs1138272 and TNF rs1800629 SNPs were associated with asthma and wheeze, respectively. 24465030

2014
dbSNP: rs1800629
rs1800629
TNF
0.030 GeneticVariation BEFREE This meta-analysis suggested that the rs1800629 polymorphism in TNF-α was a risk factor for asthma. 24936650

2014
dbSNP: rs1800629
rs1800629
TNF
0.030 GeneticVariation BEFREE To investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions. 22376040

2012
dbSNP: rs763000109
rs763000109
TNF
0.010 GeneticVariation BEFREE Our results show an association of MnSOD Ala16Val genetic polymorphism with asthma in a Serbian population and suggest a protective role of the MnSOD 16Ala allele. 25931357

2015
dbSNP: rs745738344
rs745738344
TNF
0.010 GeneticVariation BEFREE After stratification by atopic status, the heterozygous AG genotype of LT-alpha (A252G) was found to increase risk of asthma in atopic population [odds ratio (OR) = 2.00, 95% CI 1.09-3.67, p = 0.024]. 17536219

2007