rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Relationships between IC- or EC atherosclerosis and plasma tHcyt level and/or MTHFR 677C>T genotypes were analyzed after adjusting for vascular risk factors.
|
20825473 |
2011 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Hyperhomocysteinaemia, a risk factor for atherosclerosis, is common in dialysis patients and particularly in those homozygous for a common polymorphism in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene (C677T transition).
|
11865092 |
2002 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
High plasma homocysteine, a risk factor for atherosclerosis, is frequently caused by a common mutation in the gene for the enzyme, 5,10-methylenetetrahydrofolate reductase (MTHFR), C677T (alanine to valine substitution) or low intake of B vitamins that affect the remethylation or transsulfuration pathways in homocysteine metabolism.
|
12204804 |
2002 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The guanine to thymine polymorphism at position 894 of the eNOS gene (resulting in a change from glutamate to aspartate [Asp] at codon 298 [Asp298]) and the methylenetetrahydrofolate reductase (MTHFR) gene polymorphism (C677T) have been reported to be associated with atherosclerosis and cardiovascular disease.
|
15494775 |
2004 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.
|
19398669 |
2009 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The severe atheromatosis group showed rates of 62.0% and 6.9% for the C677T MTHFR gene polymorphism, in heterozygous and homozygous subjects, respectively.
|
17384833 |
2007 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Associations of methylenetetrahydrofolate reductase C677T polymorphism with markers of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.
|
17934972 |
2008 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We measured plasma high-sensitive C-reactive protein (hs-CRP) levels and screened for the C677T polymorphism of the 5-10 methylenetetrahydrofolate reductase gene (MTHFR), which is considered a genetic risk factor for atherosclerosis, by HinfI digestion.
|
15764293 |
2005 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with reduced enzyme activity, hyperhomocysteinaemia and increased risk for atherosclerosis in homozygotes.
|
11094304 |
2000 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Atherosclerosis in male patients with ankylosing spondylitis: the relation with methylenetetrahydrofolate reductase (C677T) gene polymorphism and plasma homocysteine levels.
|
23247802 |
2013 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study aimed at assessing the effect of folic acid supplementation quantitatively in each MTHFR C677T genotype and considered the efficiency of tailor-made prevention of atherosclerosis.
|
15895286 |
2005 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Smoking confers a MTHFR 677C>T genotype-dependent risk for systemic atherosclerosis: results from a large number of elderly autopsy cases that died in a community-based general geriatric hospital.
|
19403988 |
2009 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
One putative determinant of PAD is the 677C>T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR), which has previously been found to associate with various diabetic complications including retinopathy, nephropathy, atherosclerosis and coronary heart disease.
|
16274479 |
2005 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the frequency of C677T methylenetetrahydrofolate reductase (MTHFR) mutation in healthy Croatian volunteers and in patients with atherosclerosis.
|
12927690 |
2003 |