rs4986790
|
|
|
0.090 |
GeneticVariation |
BEFREE |
1400 participants (mean age: 63 years, 31% female) in the Southampton Atherosclerosis Study were genotyped for the TLR4 Asp299Gly polymorphism using the tetra-primer PCR method.
|
12957699 |
2003 |
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage renal disease.
|
16364824 |
2005 |
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Atherosclerosis in male patients with ankylosing spondylitis: the relation with methylenetetrahydrofolate reductase (C677T) gene polymorphism and plasma homocysteine levels.
|
23247802 |
2013 |
rs1232898090
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.
|
12765972 |
2003 |
rs5361
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
rs1458766475
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
rs137852912
|
|
|
0.030 |
GeneticVariation |
BEFREE |
D374Y gain-of-function mutations in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene cause severe autosomal dominant hypercholesterolemia and accelerates atherosclerosis in humans.
|
23283366 |
2013 |
rs879254925
|
|
|
0.020 |
GeneticVariation |
BEFREE |
D374Y gain-of-function mutations in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene cause severe autosomal dominant hypercholesterolemia and accelerates atherosclerosis in humans.
|
23283366 |
2013 |
rs877087
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs877087 and rs2229116 of RYR3 gene are associated with atherosclerosis severity in Japanese.
|
24423397 |
2014 |
rs662
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Q192R was more strongly associated with PCOS than previously suggested atherosclerosis risk markers.
|
30900463 |
2019 |
rs118204057
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A 60-y-old chylomicronemia patient homozygous for missense mutation (G188E) in the lipoprotein lipase gene showed no accelerated atherosclerosis.
|
17854791 |
2008 |
rs699
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A missense gene mutation with methione-to-threonine amino acid substitution at codon 235 (M235T) of angiotensinogen (AGT) has been associated with higher plasma AGT levels and may influence the pathogenesis of cardiac hypertrophy and atherosclerosis.
|
10342781 |
1999 |
rs1800562
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A prospective study of coronary heart disease and the hemochromatosis gene (HFE) C282Y mutation: the Atherosclerosis Risk in Communities (ARIC) study.
|
11257277 |
2001 |
rs16139
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A rather common leucine7-to-proline7 (Leu7Pro) polymorphism in the preproneuropeptide Y (prepro-NPY) gene signal peptide may be important in blood pressure regulation, cholesterol metabolism and the pathogenesis of atherosclerosis in humans.
|
11689216 |
2001 |
rs1282382243
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A rather common leucine7-to-proline7 (Leu7Pro) polymorphism in the preproneuropeptide Y (prepro-NPY) gene signal peptide may be important in blood pressure regulation, cholesterol metabolism and the pathogenesis of atherosclerosis in humans.
|
11689216 |
2001 |
rs8042271
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A recently identified locus for coronary artery disease (CAD) tagged by rs8042271 is in a region of tight linkage disequilibrium (LD) between 2 genes (MFGE8, ABHD2) previously linked to atherosclerosis.
|
30861420 |
2019 |
rs4142986
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A sequence variant in COL15A1 that is significantly associated with atherosclerosis (rs4142986, P = 0.017, OR = 1.434) was methylated and methylation of the risk allele correlated with decreased gene expression and increased atherosclerosis in human aorta.
|
23912340 |
2013 |
rs7439293
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A single-nucleotide polymorphism (SNP) in the palladin gene (PALLD, rs7439293) has recently been reported to be associated with coronary heart disease (CHD) in two case-control studies as well as in a large population-based cohort (Atherosclerosis Risk in Communities study, ARIC).
|
21054356 |
2011 |
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ADRB2 Arg16Gly polymorphism, lung function, and mortality: results from the Atherosclerosis Risk in Communities study.
|
17356698 |
2007 |
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
All 1085 incident coronary heart disease cases, all 300 incident ischemic stroke cases, and 1065 reference individuals from the Atherosclerosis Risk in Communities study were genotyped for the T-786C and E298D polymorphisms in NOS3.
|
17108813 |
2006 |
rs185847354
|
|
|
0.010 |
GeneticVariation |
BEFREE |
All the subjects carrying I164T mutation showed some feature of metabolic syndrome, including hypertension, hyperlipidemia, diabetes, and atherosclerosis.
|
12086969 |
2002 |
rs2043211
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, a subgroup of patients with no history of CV events (n=276) was assessed for the potential influence of the rs2043211 variant in the development of subclinical atherosclerosis, by measurement of carotid intima-media thickness (IMT) and presence of carotid plaques.
|
23088220 |
2013 |
rs1535045
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, the CD40 rs1535045 gene variant may influence development of subclinical atherosclerosis in RA patients.
|
23166616 |
2012 |
rs1008438
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An analysis was made of the association of two single nucleotide polymorphisms (db rs1008438 -110A/C and db rs1043618 +190 G/C) with circulating and intragranulocytic HSPA1A and the risk of atherosclerosis.
|
22328194 |
2012 |
rs1043618
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An analysis was made of the association of two single nucleotide polymorphisms (db rs1008438 -110A/C and db rs1043618 +190 G/C) with circulating and intragranulocytic HSPA1A and the risk of atherosclerosis.
|
22328194 |
2012 |