Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE Together with the common KCNE1 variant S38G, previously proposed as a genetic modifier of AF, HCN4-P883R may provide a substrate for the development of AF and TIC. 31481236

2019

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE The G38S polymorphism in the KCNE1 gene can significantly increase the risk of AF in both Chinese and white. 28640127

2017

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE The incidence of AF among the senior Uygur population in Xinjiang territory was correlated with the KCNE1 (G38S) polymorphism, which may be an independent risk factor for Uygur AF patients. 26662381

2015

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE KCNE1 112G>A may be useful as a biomarker for predicting the development of AF. 25366730

2014

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE This study confirmed the association of the 112G>A polymorphism and postoperative AF in a cohort of patients undergoing cardiac surgery. 24439990

2014

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE The rs1805127 polymorphism (A>G) of KCNE1 is associated with an increased risk of AF, which suggests the rs1805217 polymorphism of KCNE1 gene may play an important role in the pathogenesis of AF. 23874724

2013

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE KCNE1 G38S genetic polymorphism was determined between 237 non-valvular atrial fibrillation cases and 237 control subjects using PCR-RFLP. 23129484

2012

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE We also found that rs1805127 was associated with left atrial diameter and left ventricular end diastolic diameter in AF patients (χ(2)=24.883, p<0.001; χ(2)=34.901, p<0.001, respectively). 23020083

2012

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE Genotypes at the AF-associated loci in KCNE1 (S38G) and SCN5A (H558R) were determined by direct DNA sequencing. 19305639

2009

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE The minor allele frequencies of P448R, R519H, G643S for KCNQ1 and G38S and D85N for KCNE1 in the AF group, the community control group and the ward control group were 9.9, 7.9, 9.3%; 0, 0, -; 4.3, 4.2, 1.7%; 28.4, 31.7, 29.7%; 0.7, 0.4%, -, respectively. 17016049

2007

dbSNP: rs1805127
rs1805127
0.100 GeneticVariation BEFREE G38S polymorphism in the MinK gene could be used as a genetic marker of risk of lone AF. 17165161

2006